Advisor to industry.
Given his expertise in the neuroscience of sleep and sleep disorders, as well as his his experience as an entrepreneur founding, developing and selling a medical device company, Dr. Nofzinger has been widely consulted by industry for guidance.
Case Studies
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Case Study: Pharma Startup
• Provided strategic direction to a West Coast based Pharmaceutical startup company in the discovery & development of agents known to regulate sleep/wake CNS circuits & thereby play pivotal Therapeutic Roles in sleep/wake disorders
• Assisted in the development of Sleep/wake drugs (one clinical-stage asset, 5+ primary targets and 5 secondary targets) in a total addressable market of $22B.
• Monotherapy and fixed-dose combination tailored Rx with superiority claims
• 10+ large co-morbid neuro-psych sleep-wake populations
• Additional focused CNS development: anxiety, substance abuse
• Directed market research and background scientific rationale for the company
• Wrote Phase 1-3 protocols in the areas of sleep disorders, anxiety disorders (including PTSD), mood disorders, substance abuse disorders and neurologic disorders for these compounds
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Case Study: Med Device
GrowingSleepDeviceCo approached Dr Nofzinger regarding expansion opportunities for their existing technology
GrowingSleepDeviceCo had established a foothold in one of the sleep device markets and wanted to explore other sleep markets for their technology
Dr Nofzinger was approached given his expertise in the sleep device area of interest, his scientific expertise in the area and his success in developing a sleep device company in the space, including FDA clearance and successful launch
• Dr. Nofzinger provided a strategic report (scientific review, development of market opportunities, project timeline to enable growth of a Medical Device company in the $15B space of sleep wearables